- Dr. Smack's Office - A place for ranting and raving about anything.
- Sable's Corner - A collection of jokes, sayings and recipes.
- Sakura No Otome - Daily craziness chronicled by Japanese girls.
- SanaVision - Small collection of Flash movies and mp3s.
- Scanned! - Jokes, games, silly stories and links.
- Schlucom - Jokes, military humor and downloadable games. Features a joke search engine to help locate specific topics.
- Sean's Website - Personal information, animations and humor.
- Selina and Barbara's Mambo Mania - Random cute things designed to please.
- Settle Down Now - Humorous, personal thoughts, observations and insight.
- Shiela Moss - Yahoo-based club and the haunt for a wanna-be humor columnist.
- Shlomi Fish - Satirical writing from Israel, featuring politics and popular culture. In English and Hebrew.
- Shounen Cheezer and Shojo Neko's Millenium - Furry animals in sailor suits and personal comment and humor.
- SillyCOM - Videos, games, downloads and links.
- SliceMessiah's Shrine to Sodaism - Mock religion combining the X-Men and fizzy drink.
- Slinkycity.com - Free jokes, cartoons, funny stories and humor for everyone to enjoy.
- Snowey's Website - Dedicated to the author's life and all the crazy things that happen.
- Society for the Prevention of Idiocy - An attempt to expose the idiocy that seems to be ever-present in life.
- Sock Monkey - Oddities and shenanigans inspired by and dedicated to sock monkeys.
- Souf Oaklin - Features an Oakland Pittsburgh, University theme.
- Spandrill Magazine - Surreal, nonsense humor, wordplay and pythonesque humor.
- Spank That Monkey - Observations and simple truths concerning human-kind.
- Spassmonkey's - Monkeys and Darwinism explored.
- spastickitten - Stories, thoughts, and ways to insult the government.
- Spidermonkeys - Personal rants, reviews and pictures.
- Sports Smile - Humorous look at sports and the career of David Legham.
- Squiddum - Dancing robots, Lamborghinis, R2-D2 as well as jokes, quiz, and links.
- Squit100 - Hand-drawn comics and Dan Quayle humor.
- Squnk Productions - Emails, pictures and links.
- Statto-JTA Publishing Corporation - A repository of comedy, quotes and oddities.
- Steeb 1014 - Humor and college-related stuff.
- Stef's Realm - Collected oddities and personal photos.
- SteveMercier.com - Humorous writings on business, technology, entertainment and travel.
- Stop the Sanity - A site that deals with many important ideas, through humour.
- Style Invitational Losers - Home of a loose band of marginally sane individuals addicted to humor contests and other outlets for their smartass shenanigans.
- Super-Soundboarding - Celebrity soundboards, movie soundboards, and music.
- SuperDunner - Comment on news, current events and sport.
- Sweet Chilli Sauce - A number of encounters with the conmen of Nigeria and their promises of instant wealth. Plus Letters, jokes and sundry junk.
- Synperz Domain - Personal humor, entertainment, and sound and picture files.
- The Second Best Page in the Universe - Satire and sarcasm from a ninja pirate.
- The Spoor of Alienjack - Bizarre and often dark humor produced by a man who claims to live on the roof of a box factory. Stories, pictorials, and some non-humorous literature.
- The State of Confusion - Pictures, links and confusing stuff.
- The Stuff - Dangerously stupid but humorously unexpected content.
- The Stupid College Kid - A broad examination of what students find to be funny.
- The Super Wacky Videos - Varied humorous videos in RealPlay or MPEG format.
- The Syko Ward - A mix of the insightful, interesting, unusual, unexplained and fun.
